An experimental brain cancer compound developed at the Oklahoma Medical Research Foundation is being used in a new study that could considerably extend the lives of glioblastoma patients.
In a study at the University of Oklahoma’s Stephenson Cancer Center, the OMRF compound OKN-007 is being combined with Temodar, the current standard-of-care medication for glioblastoma. Researchers hope to learn if it can enhance Temodar’s effectiveness for a longer period of time.
Glioblastoma is an aggressive form of brain cancer with no cure. Even with surgery and chemotherapy, patients typically live only 12-18 months after diagnosis. Only 1 in 20 glioblastoma patients will live five years.
Temodar has been proven to work, but in most cases, patients tend to become resistant to the drug after approximately three months.
In combination, OKN-007 allows Temodar to remain effective for longer with less resistance, thus extending treatment well beyond the three-month window, perhaps indefinitely, said OMRF Vice President of Technology Ventures Manu Nair.
“Several additional months of treatment with Temodar can dramatically prolong the lives of patients and keep them from enduring other grueling treatments that can compromise their immune systems,” said Nair.
OKN-007 had been in trials to determine safety and efficacy since 2013. The compound was developed by OMRF scientists Rheal Towner, Ph.D., and Robert Floyd, Ph.D., as a novel therapeutic that dramatically decreased cell proliferation (spread) and angiogenesis (formation of new blood vessels), and it turned on the process of removing damaged cells so they can’t become cancerous.
“OKN-007 has been promising, but until now, it was only used in very late-stage cancer where patients are out of other options,” said Nair. “By combining it with Temodar, it offers a longer, more effective treatment regimen.”
The new study is led by James Battiste, M.D., Ph.D., medical director of the Comprehensive Brain Tumor Program at the Stephenson Cancer Center.
An estimated 12,000 Americans are diagnosed with glioblastoma each year, according to the American Brain Tumor Foundation. The standard treatment regimen involves surgery to remove as much of the tumor as possible, followed by radiation and chemotherapy. Still, the tumor almost always grows back.
“By combining Temodar and OKN-007 following initial surgery to have the brain tumor removed, we see potential for these patients to added benefit from an existing drug already proven to work, but for a much longer period of time,” said Nair.

Linda Rakett and her fellow Blue Star Mothers of Chapter 6 love supporting the military and veterans. Rakett is a volunteer with Blue Star Mothers through RSVP of Central Oklahoma. The national organization, made up of mothers who have children serving in the military or who have served and have been honorably discharged, started in 1942 during World War II.
“Our mission is to serve and help active duty military and veterans,” said Rakett, who became a Blue Star Mother when her son joined the Army right out of high school in 2003. “We send deployment boxes to the ones serving around the world, and we try to help the veterans who are at the Veterans Administration hospital or VA Centers.”
During the Christmas season, Linda and the other mothers contact nursing homes in the area and find out how many veterans are residents. They prepare gift bags that contain socks, candy, tissues, personal greeting cards, and snacks for each veteran to share with them for Christmas. They also participate in the Marines Toys for Tots drive, help out at the Military Welcome Center at Will Rogers World Airport, and participate in Veterans Day parades.
“We do whatever we can do to help,” Rakett said. “We love helping our military and our veterans.”
To learn more about Blue Star Mothers and volunteering with RSVP of Central Oklahoma, call Laura McPheeters at 405-605-3110 or email lmcpheeters@rsvpokc.org.
Since 1973, RSVP of Central Oklahoma has helped senior adults continue to live with purpose and meaning by connecting them with rewarding community volunteer opportunities, including RSVP’s Provide-A-Ride Senior Transportation Program. RSVP is a partner of Senior Corps and the United Way of Central Oklahoma. To learn more about becoming a volunteer, call Laura McPheeters at 405.605.3110 or visit rsvpokc.org. You can also follow RSVP on Facebook at facebook.com/RSVPokc.

Laura Lynn’s Home Care Named as Provider and Employer of Choice

Laura Lynn’s Home Care announced today that it has received both the 2019 Best of Home Care® – Provider of Choice and Employer of Choice Awards from Home Care Pulse. These awards are granted only to the top-ranking home care providers, based on client and caregiver satisfaction scores gathered by Home Care Pulse.
Laura Lynn’s Home Care is now ranked among a small handful of home care providers across the country who have proven their ability to provide an exceptional working experience to employees and the highest quality care to clients.
“We want to congratulate Laura Lynn’s Home Care on receiving both the Best of Home Care – Provider of Choice Award and the Best of Home Care – Employer of Choice Award,” says Erik Madsen, CEO of Home Care Pulse.
“Since these awards are based on real, unfiltered feedback from clients and caregivers, Laura Lynn’s Home Care has proven their dedication to providing a great work environment and solid training to employees, while maintaining their focus on client satisfaction. We are pleased to recognize their dedication to quality professionalism and expertise in home care.”
Best of Home Care providers have contracted with Home Care Pulse to gather feedback from their clients and caregivers via live phone interviews each month. Because Home Care Pulse is an independent company, it is able to collect honest and unbiased feedback.
“These awards confirm what we have always believed. Our team of caregivers is the absolute best you can get. We’re so proud of their hard work, their compassion and the care they provide to the families we serve,” says Laura Hicks, CEO and founder of Laura Lynn’s Home Care.
“Our goal at Home Care Pulse is to empower home care businesses to deliver the best home care possible,” says Erik Madsen, CEO of Home Care Pulse. “We are happy to recognize Laura Lynn’s Home Care as a Best of Home Care award-winning provider and celebrate their accomplishments in building a team of happy, qualified caregivers who provide outstanding care for their clients.”
For more information about Laura Lynn’s Home Care, visit LauraLynnsHomeCare.com or call (405) 418-2961.
Established in 2002 by Laura Lynn Hicks, Laura Lynn’s Home Care is a licensed home care agency and has become Oklahoma’s premier provider of private-duty services. Laura Lynn’s Home Care provides in-home assistance delivered by a team of Certified Home Health Aides. Laura Lynn’s Home Care clients are able to remain in the comfort of their homes, while receiving long-term care or post-operative assistance.

By Joshua Vascil, OU Medicine

When it comes to healthy and effective exercise habits, the amount of time and effort you can put in to the workouts is the key. However, an OU Medicine internal medicine provider says there are some helpful options for those who don’t have much time to work out.
According to the Journal of the American Medical Association, adults should spend 150 to 300 minutes per week of moderate-intensity, or 75 to 150 minutes a week of vigorous-intensity aerobic physical activity. The Journal also recommends adults perform muscle-strengthening activities that involve all major muscle groups two or more days a week.
Joanne Skaggs, M.D., OU Medicine internal medicine physician, says time does matter when it comes to your workout habits, however, if you don’t have much time, she recommends High Intensity Interval Training or HIIT work-outs or simply limiting idle time throughout the day.
“Weight-bearing exercise is key for metabolism and losing weight just as much as aerobic physical activity is,” Skaggs said. “You always want to do a combination.”
Maintaining a routine to ensure that you get the most out of your exercise habits is important, Skaggs said. She recommends marking time for exercise on a calendar. “It forces it to become part of your schedule so that it’s harder to ignore, or at least there is some guilt. Group fitness is also a good way to motivate and become socially engaged in your community.”
For those who can’t find time or can’t make it to a fitness facility or gym regularly, Skaggs suggests trying to limit idle time by incorporating some of these activities in your day:
· Move more
· Sit less
· Park at the back of the parking lot
· Take the stairs when you can
· Incorporate physical activity into family time
· Look for fitness videos online, even if it’s only a 10 minute workout
“I always recommend the rule of 3’s,” Skaggs said. “Three minutes for three days in a row. Increase by three minutes every three days until you are able to reach 30 minutes. It’s much more doable this way.”
Skaggs warns that it’s always important everyone knows their limits and not push too hard, to avoid injury. “Do not go out and try and lift excessively or over exert yourself. Know your body. Do what you can, gradually pushing yourself to maintain a steady, healthy exercise pattern. And, you need to realize that physical fitness and health takes time. You’re not going to lose 50 pounds overnight.”
Before starting a new exercise and fitness regimen, it is important to check with your doctor.
OU Medicine has primary care physicians available at many locations across the Oklahoma City metro. For more information, go to: https://www.oumedicine.com/oumedicine/primary-care

Game Warden Nathan Erdman has been promoted to Chief of the Law Enforcement Division. Erdman previously served as Assistant Chief of the division since 2016.
The Law Enforcement Division is responsible for upholding the laws and regulations that protect Oklahoma’s wildlife resources. Game wardens are public servants sworn to protect wildlife and the public’s interests in the outdoors. These certified peace officers have statewide jurisdiction to act on any law violation. They check licenses and bag limits of hunters and anglers. Oftentimes wardens may have to wait, day or night, for long periods in concealed locations to nab the poachers who are stealing fish and game.
As Chief, Erdman oversees the division of about 120 people, the largest of the Department’s five divisions. Employees consist of Game Wardens, Game Warden Supervisors and eight District Chiefs. Headquarters staff includes an Assistant Chief, an Operations Manager and Training Supervisor, and a secretary.
“I’m just lucky I’ve got 117 of the finest employees that I could ever want,” he said. “I’m up here to work for them; trying to make sure that they have everything that they need to get their job done and get it done more efficiently.”
Erdman said he knew early in his life that he wanted to work as a game warden. “I grew up in the country, hunting and fishing.” He recalls asking his college adviser what classes would be required to become a game warden.
Erdman earned a fish and wildlife management degree at Northeastern State University, and was hired as a game warden shortly after he graduated. His first assignment was in Beaver County in the Panhandle, where he spent 13 years. He then transferred to his home Okfuskee County in 2007. A year later, he was promoted to Supervisor in District 4, where he worked until becoming assistant chief in 2016. He has worked for the Wildlife Department for 24 years.
He said becoming Chief has been somewhat surreal. “I grew up in the small town of Okemah, and graduated with 43 kids. To go from small town to being Chief of enforcement for all of Oklahoma’s Game Wardens is something you would never imagine.”
Game wardens must do their job well, as they are constantly in the public eye. They are expected to know all there is to know about hunting, fishing, wildlife laws, wildlife management, camping and other outdoor activities as well as general information about their county.
Game wardens often spend time visiting landowners in their county, encouraging them to allow ethical hunters and anglers on their land to harvest the surplus wildlife. They may assist the landowner with poaching problems or give them information about stocking fish in a pond.
Game wardens frequently help teach hunter education courses and fishing clinics. And they often help operate events for students involved in the Department’s Archery in the Schools and Shooting Sports programs. They occasionally visit with sportsmen’s clubs, schools, Scout groups and civic groups. They may speak about new laws and regulations, or about some topic directly related to hunting or fishing. They may also pass along printed information published by the Wildlife Department.

by Dr. C.V Ramana

Metabolic syndrome is a combination of risk factors that increase the likelihood of developing heart disease, diabetes, and stroke. These risk factors include high blood pressure, high blood sugar levels, excess body fat (particularly around the waist), high triglyceride levels and low levels of good cholesterol. Having only one of these risk factors does not mean that you have metabolic syndrome, however, having one will increase the possibly of developing cardiovascular disease. Having three or more will likely result in a diagnosis of metabolic syndrome. The two critical risk factors for diagnosing metabolic syndrome is excess central body fat and insulin resistance.
The American Heart Association reports that approximately 25 percent of the American population has metabolic syndrome. To diagnose metabolic syndrome your primary care provider will perform tests to look for signs of the disorder. These tests may include a baseline blood pressure measurement, waist circumference measurement, a fasting lipid panel, and a fasting glucose level. Complications of metabolic syndrome include hardening of the arteries, peripheral artery disease, cardiovascular disease, diabetes, heart attack, kidney disease and stroke.
If you think you are at risk for metabolic syndrome, see your primary care provider for an examination and screening. Metabolic syndrome is treatable and the poor outcomes related to living with the disorder for many years are avoidable. Your primary care provider can provide support and encouragement for decreasing your overall body fat by making lifestyle changes. He or she can prescribe medications to reduce high blood pressure, high blood sugar and even high cholesterol. Preventing poor outcomes from metabolic syndrome is certainly possible. Establishing a primary care provider and having regular check ups is the first step in taking control of your health and leading a healthier lifestyle.
You are also welcome to call our Vascular Center to schedule a prompt and free consultation. You can contact us at 405-608-8884. We are a specialized center staffed with highly experienced professionals, including a Vascular/Interventional physician, dedicated to treating vascular disease on an outpatient basis using the latest proven technology to combat this epidemic.
Dr. C.V Ramana is a vascular and interventional radiologist with more than 20 years of practice experience. He has expertise in all areas of vascular and interventional radiology. Dr. Ramana has a Ph.D from Yale University and MD from CWRU in Cleveland, Ohio where he subsequently completed his fellowship in Vascular and Interventional Radiology at the Cleveland Clinic.
Visit Naadi Health at 1 NW 64th Street in Oklahoma City or call (405)-608-8884. www.naadihealthcare.com

Ensemble performs woman composer Libby Larsen with Mozart, Weber, Schoenberg

Guest pianist Stephen Buck joins the Brightmusic Chamber Ensemble in this season’s third concert, “Rustic Gardens,” Tuesday, January 21, 7:30 p.m at St. Paul’s Cathedral. Brightmusic continues the season featuring female composers with “Barn Dances” by Grammy Award winner Libby Larsen, in addition to works by Weber, Mozart, and Schoenberg. Buck serves on the academic faculty of State University of New York (SUNY) Purchase Conservatory of Music and champions new music.
Cowboy dances inspired American Libby Larsen (b. 1950) to write “Barn Dances” for flute, clarinet, and piano. Larsen named each movement for a dance step “to take a flight of fancy in each movement and to create the musical equivalent of a calendar drawing.” The second movement, Divide the Ring, pays homage to country singer Gene Autry.
“Rustic Gardens” continues with the Quintet for Clarinet and Strings in B-flat major (Op. 34) by German composer Carl Maria von Weber (1786-1826) and the Quartet No. 1 for Flute and Strings in D major (K. 285) by Wolfgang Amadeus Mozart (1756-1791). Weber had his friend, clarinet virtuoso Heinrich Baermann, in mind, with rich technical and melodic passages for the soloist. Mozart likewise wrote his quartet for Dutch surgeon and flutist Ferdinand Dejean. The quartet charms with clear form and texture.
In contrast is the harmonically complex Chamber Symphony No. 1 by Austrian Arnold Schoenberg (1874-1951). The piece marks the end of his conventional (post-Romantic) period and anticipates his evolution to a twelve-tone technique, giving equal emphasis to all notes.
Musicians appearing in this concert are: Stephen Buck (piano), Gregory Lee and Katrin Stamatis (violin), Mark Neumann (viola), Jonathan Ruck (cello), Parthena Owens, (flute), and Chad Burrow (clarinet).
Admission is $20 at the door and free for children, active-duty military, and students with ID.
Brightmusic Chamber Ensemble, Oklahoma City’s own chamber ensemble, presents fine classical chamber music in acoustically-rich St. Paul’s Cathedral at NW 7th and Robinson near downtown Oklahoma City. Free parking is available south of the cathedral. For more information about the ensemble and upcoming concerts, visit www.brightmusic.org

Dear Savvy Senior,

A couple months back I read that the IRS will be offering a new senior-friendly tax form this tax season that will be easier to use. What can you tell me about this? Paper Filer

Dear Filer,
It’s true. The Internal Revenue Service (IRS) has created a new federal income-tax form specifically designed for senior taxpayers, age 65 and older, that should make filing a little easier this year, particularly those who don’t file electronically. Here’s what you should know.
Form 1040-SR
Created by the 2018 Bipartisan Budget Act, the new two-page simplified federal income tax form is called the 1040-SR. Similar in style to the old 1040-EZ form that the IRS discontinued last year, the new 1040-SR has larger print and better color contrast that makes it easier to read.
In addition, it also includes a chart to help older taxpayers calculate their standard deduction, which may help ensure that fewer seniors neglect to take the additional standard deduction that they are entitled to. For 2019, the additional deduction for those 65 or older or the blind is $1,300.
The 1040-SR form also has specific lines for retirement income streams such as Social Security benefits, IRA distributions, pensions and annuities, along with earned income from work wages and tips. And, it allows a child tax credit for seniors who are still taking care of a dependent child or grandchild.
You can also report capital gains and losses, as well as interest and dividends on this new form. Any of the tax schedules available to those using the standard form 1040 may also be used with the 1040-SR.
You should also know that the 1040-SR doesn’t put a limit on interest, dividends, or capital gains, nor does it cap overall income like the old 1040-EZ form did. But, if you have to itemize because of state and local taxes or charitable giving, then you will not be able to use the new Form 1040-SR.
Paper Filing Advantage
Seniors who use tax-preparation software to file their taxes will be able to generate a 1040-SR, but the new form will provide the most significant benefit to taxpayers who still fill out and file their returns on paper.
Last year, about 88 percent of the 153 million individual federal tax returns filed to the IRS were filed electronically. About 5 percent were prepared using tax software, then printed out and mailed to the agency, while about 7 percent were prepared on paper.
To use the new 1040-SR tax form for the 2019 filing year, taxpayers, including both spouses if filing jointly, must be at least age 65 before Jan. 1, 2020. You also don’t have to be retired to use the form – older workers can use it too. But early retirees (younger than 65) cannot use 1040-SR.
To see the 2019 draft version of the new 1040-SR form, go to IRS.gov/pub/irs-dft/f1040s–dft.pdf.
Tax Preparation Help
If you need help filing your tax returns this year, consider contacting the Tax Counseling for the Elderly (or TCE) program. Sponsored by the IRS, TEC provides free tax preparation and counseling to middle and low-income taxpayers, age 60 and older. Call 800-906-9887 or visit IRS.treasury.gov/freetaxprep to locate a service near you.
Also check with AARP, a participant in the TCE program that provides free tax preparation at more than 4,800 sites nationwide. To locate an AARP Tax-Aide site call 888-227-7669 or visit AARP.org/findtaxhelp. You don’t have to be an AARP member to use this service.

Send your senior questions to: Savvy Senior, P.O. Box 5443, Norman, OK 73070, or visit SavvySenior.org. Jim Miller is a contributor to the NBC Today show and author of “The Savvy Senior” book.