An experimental brain cancer compound developed at the Oklahoma Medical Research Foundation is being used in a new study that could considerably extend the lives of glioblastoma patients.
In a study at the University of Oklahoma’s Stephenson Cancer Center, the OMRF compound OKN-007 is being combined with Temodar, the current standard-of-care medication for glioblastoma. Researchers hope to learn if it can enhance Temodar’s effectiveness for a longer period of time.
Glioblastoma is an aggressive form of brain cancer with no cure. Even with surgery and chemotherapy, patients typically live only 12-18 months after diagnosis. Only 1 in 20 glioblastoma patients will live five years.
Temodar has been proven to work, but in most cases, patients tend to become resistant to the drug after approximately three months.
In combination, OKN-007 allows Temodar to remain effective for longer with less resistance, thus extending treatment well beyond the three-month window, perhaps indefinitely, said OMRF Vice President of Technology Ventures Manu Nair.
“Several additional months of treatment with Temodar can dramatically prolong the lives of patients and keep them from enduring other grueling treatments that can compromise their immune systems,” said Nair.
OKN-007 had been in trials to determine safety and efficacy since 2013. The compound was developed by OMRF scientists Rheal Towner, Ph.D., and Robert Floyd, Ph.D., as a novel therapeutic that dramatically decreased cell proliferation (spread) and angiogenesis (formation of new blood vessels), and it turned on the process of removing damaged cells so they can’t become cancerous.
“OKN-007 has been promising, but until now, it was only used in very late-stage cancer where patients are out of other options,” said Nair. “By combining it with Temodar, it offers a longer, more effective treatment regimen.”
The new study is led by James Battiste, M.D., Ph.D., medical director of the Comprehensive Brain Tumor Program at the Stephenson Cancer Center.
An estimated 12,000 Americans are diagnosed with glioblastoma each year, according to the American Brain Tumor Foundation. The standard treatment regimen involves surgery to remove as much of the tumor as possible, followed by radiation and chemotherapy. Still, the tumor almost always grows back.
“By combining Temodar and OKN-007 following initial surgery to have the brain tumor removed, we see potential for these patients to added benefit from an existing drug already proven to work, but for a much longer period of time,” said Nair.

Linda Rakett and her fellow Blue Star Mothers of Chapter 6 love supporting the military and veterans. Rakett is a volunteer with Blue Star Mothers through RSVP of Central Oklahoma. The national organization, made up of mothers who have children serving in the military or who have served and have been honorably discharged, started in 1942 during World War II.
“Our mission is to serve and help active duty military and veterans,” said Rakett, who became a Blue Star Mother when her son joined the Army right out of high school in 2003. “We send deployment boxes to the ones serving around the world, and we try to help the veterans who are at the Veterans Administration hospital or VA Centers.”
During the Christmas season, Linda and the other mothers contact nursing homes in the area and find out how many veterans are residents. They prepare gift bags that contain socks, candy, tissues, personal greeting cards, and snacks for each veteran to share with them for Christmas. They also participate in the Marines Toys for Tots drive, help out at the Military Welcome Center at Will Rogers World Airport, and participate in Veterans Day parades.
“We do whatever we can do to help,” Rakett said. “We love helping our military and our veterans.”
To learn more about Blue Star Mothers and volunteering with RSVP of Central Oklahoma, call Laura McPheeters at 405-605-3110 or email lmcpheeters@rsvpokc.org.
Since 1973, RSVP of Central Oklahoma has helped senior adults continue to live with purpose and meaning by connecting them with rewarding community volunteer opportunities, including RSVP’s Provide-A-Ride Senior Transportation Program. RSVP is a partner of Senior Corps and the United Way of Central Oklahoma. To learn more about becoming a volunteer, call Laura McPheeters at 405.605.3110 or visit rsvpokc.org. You can also follow RSVP on Facebook at facebook.com/RSVPokc.

By MC1 Jeffrey Hanshaw, SurgeMain Public Affairs

Assistant Secretary of the Navy for Manpower and Reserve Affairs Greg Slavonic visited Pearl Harbor Dec. 7, to speak personally with shipyard workers at an all-hands call and make public remarks at the USS Oklahoma Memorial on the anniversary of the World War II bombing.
Slavonic’s visit is in the wake of the deaths of two Pearl Harbor Naval Shipyard & Intermediate Maintenance Facility workers Dec. 5.
“The Pearl Harbor Naval Shipyard proved its tremendous spirit and resilience in the second World War when it responded to the tragic bombing,” Slavonic said. “In a mighty and skillful effort, USS Oklahoma was righted and refloated. Sadly, tragedy is upon us again—and we are here to remember the fallen from the past and from the recent present.”
Slavonic is responsible for the overall supervision and oversight of manpower and reserve component affairs of the department of the Navy including the development of programs and policy related to active, reserve, retired military personnel, their family members, and the civilian workforce; the tracking of the contractor workforce, and, the oversight of human resources systems within the department.
With the recent deaths fresh in everyone’s mind, Secretary Slavonic addressed a crowd of USS Oklahoma family members, World War II veterans and others, speaking on how the heroes of Pearl Harbor, both past and present, have always showed great resolve in the face of trials. “It’s hard to imagine what that day was like,” he said, referring to the attack on Pearl Harbor, an event that thrust the United States into World War II.
A retired U.S. Navy rear admiral and Oklahoma native, Slavonic enlisted as a signalman, eventually entered the Navy Reserve, and then retired after serving 34 years. He acknowledged the presence of another Sailor and World War II veteran in attendance at the ceremony: Signalman 2nd Class Burke Waldron. “I met a young man who is 96 years young and we have something in common,” Slavonic said, denoting their shared rating of signalman. “It was the bright spot of a difficult day.”
The memorial he stood before contains the names of those lost on the USS Oklahoma with each Sailor and Marine who perished represented by a marble pillar. Slavonic served on the committee that led the effort to build the memorial. He went on to describe how it is a visual representation of Sailors manning the rails, referring to how the erect marble pillars mirror sailors lining the deck of a ship to salute and render honors. “The greatest generation is recognized by this memorial,” he said, gesturing to the pillars.
“The men and women today, in uniform and out,” he said in closing, “embody the proud heritage and fighting spirit of the crew of Oklahoma and those who were determined to make her stand upright again. Their legacy lives on, their story will not die.”

By Joshua Vascil, OU Medicine

When it comes to healthy and effective exercise habits, the amount of time and effort you can put in to the workouts is the key. However, an OU Medicine internal medicine provider says there are some helpful options for those who don’t have much time to work out.
According to the Journal of the American Medical Association, adults should spend 150 to 300 minutes per week of moderate-intensity, or 75 to 150 minutes a week of vigorous-intensity aerobic physical activity. The Journal also recommends adults perform muscle-strengthening activities that involve all major muscle groups two or more days a week.
Joanne Skaggs, M.D., OU Medicine internal medicine physician, says time does matter when it comes to your workout habits, however, if you don’t have much time, she recommends High Intensity Interval Training or HIIT work-outs or simply limiting idle time throughout the day.
“Weight-bearing exercise is key for metabolism and losing weight just as much as aerobic physical activity is,” Skaggs said. “You always want to do a combination.”
Maintaining a routine to ensure that you get the most out of your exercise habits is important, Skaggs said. She recommends marking time for exercise on a calendar. “It forces it to become part of your schedule so that it’s harder to ignore, or at least there is some guilt. Group fitness is also a good way to motivate and become socially engaged in your community.”
For those who can’t find time or can’t make it to a fitness facility or gym regularly, Skaggs suggests trying to limit idle time by incorporating some of these activities in your day:
· Move more
· Sit less
· Park at the back of the parking lot
· Take the stairs when you can
· Incorporate physical activity into family time
· Look for fitness videos online, even if it’s only a 10 minute workout
“I always recommend the rule of 3’s,” Skaggs said. “Three minutes for three days in a row. Increase by three minutes every three days until you are able to reach 30 minutes. It’s much more doable this way.”
Skaggs warns that it’s always important everyone knows their limits and not push too hard, to avoid injury. “Do not go out and try and lift excessively or over exert yourself. Know your body. Do what you can, gradually pushing yourself to maintain a steady, healthy exercise pattern. And, you need to realize that physical fitness and health takes time. You’re not going to lose 50 pounds overnight.”
Before starting a new exercise and fitness regimen, it is important to check with your doctor.
OU Medicine has primary care physicians available at many locations across the Oklahoma City metro. For more information, go to: https://www.oumedicine.com/oumedicine/primary-care

Photography and Text by Terry “Travels with Terry” Zinn t4z@aol.com

Any time of year is a good time to look toward the future while examining the past. Over my more than twenty-five years of professional travel writing and photography I find some of my most carefree experiences had been aboard a ship traveling to unknown destinations.
Over the years I have cruised aboard Regent, Royal Viking (twice), Holland American, MS Egypt, Sunline, Blount, Princess, Seabourn, The American Heritage Windjammer, and a Fantom ship to Cuba, among others. These personal experiences add credibility to my evaluations of the cruise experience. I often tell my friends that on the whole I find the cruise ship experience so good that I’d do it every week, if it weren’t for the single supplement penalty. Paying for two while I’m a single traveler is not appealing. Some cruise lines will try and pair you with a compatible stranger to negate the double charge, but that uncertainly is not for me.
There is a never-ending assortment of cruises ships, small to mega sized, all with advantages and disadvantages. Large mega ships offer a wider range of dining options, some with elite specialty pre reserved dinning rooms with up charges, but often worth the upscale food selections and air of luxury. Of course, when you share your leisure experiences with two or three thousand of your best strangers, with or without children and other walkers, can be a roadblock to carefree cruising. While the ships try their best not to have log jams during tour disembarkations, and final disembarkation, the wait is a challenger for impatient passengers. Larger ocean-going ships promise and offer a smoother sailing with the weather is not cooperating.
Smaller ships are more at prey to unwieldy seas, but most captains will steer away from such irritations if possible. The key is if possible, as the Captain is in charge of your safety as well as your enjoyment or frustrations, despite your wishes, as some planned on ports of call have to be substituted without notice. Other less offered options are historical lectures and smaller entertainment options as well as less shopping and casino. I can do without casinos, but some find it a must for evening entertainment.
You still have lots of options when exploring the ship your wish to book, including dining times, cabin locations, beverage packages, and optional upscale booking venues such as spas, relaxation areas, and on deck venues.
I find on cruises you get what you pay for. On an upcoming cruise with Celebrity I booked the aqua class ocean view cabin with concierge service and a beverage package and even room service which is so welcomed early in the morning. This is a regular size cabin with small veranda and is not the next class up a suite. The difference in price from a non Aqua class deck to a lower deck, same size room and veranda, was nominal. For the perks of the higher class, it made good sense to spend a little more and get a lot more luxury. I find this true on other cruise lines as well.
In our internet age, there are many cruise ship’s tours and reviews on line. Just put in the name of the cruise line or specified ship and you might be surprised at the honest and informative evaluations, some with cruise ship video tours.
Don’t let all these prepaid and prereserved options daunt you. It does take up your time and mental energies but that can be part of the cruise enjoyment. I have always found there are three levels of travel enjoyment. One is the pre-trip, planning and looking forward to an adventure. Two is the trip or destination itself. And three is reflecting, some time for years on your travel experience. All three levels amplify your benefits from travel.
It is well known that a prime advantage of a cruise is arrive, unpack once, and your basic needs, including food and entertainment, is taken care. Just as in any hotel, large or small, upscale or not, the noise irritation of door slamming from your “neighbors” is inevitable.
It this does not fit your disposition, maybe leisure travel is not for you. Travel is a risk, from a secure home base, but if you never challenge yourself to get out into the world, you become only an armchair traveler watching travel shows on TV. If health allows go as soon as you can as the world and its challenges are always increasing, and besides, I don’t think we are getting any younger or more mobile. But with an adventurous spirit and not expecting too much, travel can be a reward for your spirit and your pocketbook.

For your consideration: https://okveterannews.com/031215/travel-entertainment-reflections-on-a-visit-to-cuba-part-two-getting-there

Mr. Terry Zinn – Travel Editor
Past President: International Food Wine and Travel Writers Association
3110 N.W. 15 Street – Oklahoma City, OK 73107
https://realtraveladventures.com/?s=terry+zinn
https://realtraveladventures.com/?s=zinn
http://new.okveterannews.com/?s=TERRY+ZINN
www.martinitravels.com

Game Warden Nathan Erdman has been promoted to Chief of the Law Enforcement Division. Erdman previously served as Assistant Chief of the division since 2016.
The Law Enforcement Division is responsible for upholding the laws and regulations that protect Oklahoma’s wildlife resources. Game wardens are public servants sworn to protect wildlife and the public’s interests in the outdoors. These certified peace officers have statewide jurisdiction to act on any law violation. They check licenses and bag limits of hunters and anglers. Oftentimes wardens may have to wait, day or night, for long periods in concealed locations to nab the poachers who are stealing fish and game.
As Chief, Erdman oversees the division of about 120 people, the largest of the Department’s five divisions. Employees consist of Game Wardens, Game Warden Supervisors and eight District Chiefs. Headquarters staff includes an Assistant Chief, an Operations Manager and Training Supervisor, and a secretary.
“I’m just lucky I’ve got 117 of the finest employees that I could ever want,” he said. “I’m up here to work for them; trying to make sure that they have everything that they need to get their job done and get it done more efficiently.”
Erdman said he knew early in his life that he wanted to work as a game warden. “I grew up in the country, hunting and fishing.” He recalls asking his college adviser what classes would be required to become a game warden.
Erdman earned a fish and wildlife management degree at Northeastern State University, and was hired as a game warden shortly after he graduated. His first assignment was in Beaver County in the Panhandle, where he spent 13 years. He then transferred to his home Okfuskee County in 2007. A year later, he was promoted to Supervisor in District 4, where he worked until becoming assistant chief in 2016. He has worked for the Wildlife Department for 24 years.
He said becoming Chief has been somewhat surreal. “I grew up in the small town of Okemah, and graduated with 43 kids. To go from small town to being Chief of enforcement for all of Oklahoma’s Game Wardens is something you would never imagine.”
Game wardens must do their job well, as they are constantly in the public eye. They are expected to know all there is to know about hunting, fishing, wildlife laws, wildlife management, camping and other outdoor activities as well as general information about their county.
Game wardens often spend time visiting landowners in their county, encouraging them to allow ethical hunters and anglers on their land to harvest the surplus wildlife. They may assist the landowner with poaching problems or give them information about stocking fish in a pond.
Game wardens frequently help teach hunter education courses and fishing clinics. And they often help operate events for students involved in the Department’s Archery in the Schools and Shooting Sports programs. They occasionally visit with sportsmen’s clubs, schools, Scout groups and civic groups. They may speak about new laws and regulations, or about some topic directly related to hunting or fishing. They may also pass along printed information published by the Wildlife Department.

The trauma center at OU Medicine has been re-verified as a Level 1 Trauma Center by the American College of Surgeons.
In 2001, the Trauma One Center, at both OU Medical Center and The Children’s Hospital, was designated as Oklahoma’s only Level 1 Trauma Center, the highest national ranking a trauma center can receive. The verification process by the American College of Surgeons validates that trauma centers have all resources necessary for any type of trauma care.
“Earning verification from the American College of Surgeons is gratifying because it reflects the commitment and hard work that our healthcare professionals deliver day in and day out,” said OU Medical Center President Kris Gose. “The process validates that we have all resources in place to provide optimal trauma care at any time.”
As a Level 1 Trauma Center, Trauma One offers comprehensive care that can handle the most critical emergencies. Trauma One provides 24-hour coverage by general surgeons, and quick availability of care in specialties such as orthopedic surgery, neurosurgery, anesthesiology, emergency medicine, radiology, internal medicine, plastic surgery, oral and maxillofacial surgery and more.
Operating rooms and trauma surgeons are available 365 days a year, and the air ambulance Medi Flight can be dispatched in minutes to airlift patients to Trauma One. A multidisciplinary team of physicians, nurses, specialists and other health care professionals are always on site, using advanced technology to treat the most severe and critical injuries. Level 1 Trauma Centers provide total care for every aspect of injury, from prevention through rehabilitation.
In addition to serving people across Oklahoma, Trauma One, because of its location in the geographic center of the state, is ideally positioned for regional access as well. An injured person’s best chance for survival is when treatment occurs within an hour of the event. Paramedics, ambulance systems and other hospitals across the state play key roles in transporting patients to Trauma One within an hour.
“The Trauma One Center has been able to save countless lives in its nearly 20-year existence,” said Roxie Albrecht, M.D., medical director of Trauma One. “As part of a tertiary care center, it is important that we participate in continuous assessment of our program. Our aim is to always provide the highest level of care to people when they need it the most.”
The verification of Trauma One was conducted by the Verification Review Committee, a subcommittee of the Committee on Trauma of the American College of Surgeons. Verified trauma centers must meet the essential criteria that ensure trauma care capability and institutional performance, as outlined by the American College of Surgeons’ Committee on Trauma in its manual Resources for Optimal Care of the Injured Patient. There are five categories of verification in the program. In addition to submitting documentation, Trauma One had an on-site review by a team of experienced site reviewers.
Level 1 Trauma Centers like OU’s Trauma One also provide public education and prevention information to people across the state. OU’s primary areas of advocacy are: ATV Ride Safe Oklahoma, which provides classes to increase awareness of ATV safety guidelines; Stop the Bleed, a course that teaches how to save someone’s life by controlling bleeding; and concussion education for coaches, game officials, athletes and parents about the nature of concussion and head injury.

Ensemble performs woman composer Libby Larsen with Mozart, Weber, Schoenberg

Guest pianist Stephen Buck joins the Brightmusic Chamber Ensemble in this season’s third concert, “Rustic Gardens,” Tuesday, January 21, 7:30 p.m at St. Paul’s Cathedral. Brightmusic continues the season featuring female composers with “Barn Dances” by Grammy Award winner Libby Larsen, in addition to works by Weber, Mozart, and Schoenberg. Buck serves on the academic faculty of State University of New York (SUNY) Purchase Conservatory of Music and champions new music.
Cowboy dances inspired American Libby Larsen (b. 1950) to write “Barn Dances” for flute, clarinet, and piano. Larsen named each movement for a dance step “to take a flight of fancy in each movement and to create the musical equivalent of a calendar drawing.” The second movement, Divide the Ring, pays homage to country singer Gene Autry.
“Rustic Gardens” continues with the Quintet for Clarinet and Strings in B-flat major (Op. 34) by German composer Carl Maria von Weber (1786-1826) and the Quartet No. 1 for Flute and Strings in D major (K. 285) by Wolfgang Amadeus Mozart (1756-1791). Weber had his friend, clarinet virtuoso Heinrich Baermann, in mind, with rich technical and melodic passages for the soloist. Mozart likewise wrote his quartet for Dutch surgeon and flutist Ferdinand Dejean. The quartet charms with clear form and texture.
In contrast is the harmonically complex Chamber Symphony No. 1 by Austrian Arnold Schoenberg (1874-1951). The piece marks the end of his conventional (post-Romantic) period and anticipates his evolution to a twelve-tone technique, giving equal emphasis to all notes.
Musicians appearing in this concert are: Stephen Buck (piano), Gregory Lee and Katrin Stamatis (violin), Mark Neumann (viola), Jonathan Ruck (cello), Parthena Owens, (flute), and Chad Burrow (clarinet).
Admission is $20 at the door and free for children, active-duty military, and students with ID.
Brightmusic Chamber Ensemble, Oklahoma City’s own chamber ensemble, presents fine classical chamber music in acoustically-rich St. Paul’s Cathedral at NW 7th and Robinson near downtown Oklahoma City. Free parking is available south of the cathedral. For more information about the ensemble and upcoming concerts, visit www.brightmusic.org

When you hear the word “malnutrition,” you probably think of people in impoverished countries, but the fact is, one in every two older adults is at risk of becoming malnourished.
An elderly Oklahoma City woman was that one in two. Sharon Gibson said she was wasting away. Doctors had given up hope and so had she.
“It was just all overwhelming and I was to the point where I didn’t care whether I lived or died,” the 74-year-old said.
Malnutrition in older adults is a hidden and growing epidemic and a costly one. The estimated price tag of the increased health care costs for disease-associated malnutrition in older U.S. adults tops $51 Billion a year. Hunger is not the sole cause. Sometimes it’s about eating the wrong foods and sometimes medical conditions like cancer, diabetes and Alzheimer’s are to blame.
Gibson had been diagnosed with Chronic Obstructive Pulmonary Disease, which left her constantly out of breath. She also had digestive issues that impacted her ability to eat, as well as trouble standing, which made it difficult to cook.
“I was very sick physically, emotionally. I couldn’t eat. My digestive system was shot. My lungs were shot – my whole bone structure. I couldn’t even stand up straight,” she explained. That was before Gibson found Valir Pace, a non-profit program that provides all-inclusive care to older adults.
“A lot of participants have come to me when I’m doing their initial assessment and they say, ‘you know, sometimes I have to pay my medicine, you know, pay for medicine and sometimes I have to decide if I want to eat or what I’m going to buy to eat and that’s so heartbreaking,” said Zella Classen, MA, RD/LD, director of Food and Nutrition at Valir Pace.
At Pace, Classen and the entire nutrition team spend their days preparing, serving and packing meals for delivery to participants. They know malnutrition in older adults can lead to a variety of health problems. These include:
• An increased risk of infection due to a weak immune system
• Poor wound healing
• Muscle weakness and decreased bone mass, which increases the risk of falls and fractures
• A higher risk of hospitalization and death
“A lot of times someone will come to me and they may not have been educated on an appropriate diet for them. And remember, as we are get older, we may develop a chronic disease like diabetes or heart disease, and things like that; and they may not have been educated on that. Or if they have been, they really struggle on getting the right foods for that diet because of their limited income. So, we try to work with them on educating and then trying to help solve that problem on getting them the appropriate foods,” Classen said.
Today thanks to Valir Pace, participants have access to two meals a day, as well as delivery of specially prepared meals and groceries to their homes. It’s not just providing food, though. Classen said it is about providing the right food and the right nutritional supplements to optimize health.
Today, Gibson has a very different outlook on life.
“Nutrition is the basis of everything. If you’re not eating, your body isn’t functioning. You can’t do anything else. So, Zella interviewed me and asked really good questions. They got to the root of my digestive problems and set up a plan with me and, slow but sure, I gathered strength,” she said.
Gibson pays nothing for the program – a program she says has literally saved her life.
“They’ve turned my life around. I’m living again. I’m not just existing. I’m not waiting to die. I’m living and enjoying each day,” she said.
To find out if you or a loved one qualifies for the program, visit www.valirpace.org