Two Oklahoma Medical Research Foundation scientists have received Merit Review Awards totaling $1.3 million from the U.S. Department of Veterans Affairs.
Holly Van Remmen, Ph.D., and Tim Griffin, Ph.D., from OMRF’s Aging and Metabolism Research Program focus on a pair of diseases prevalent in aging veterans: age-related muscle loss and osteoarthritis, respectively.
Van Remmen, who chairs OMRF’s aging program, received $650,000 to continue an investigation into a potential therapy for age-related muscle loss called sarcopenia. No drug options currently exist to treat the condition, which causes muscle weakness and atrophy.
“Sarcopenia is a highly relevant problem for the veteran population, as more than half of all veterans are over age 60,” said Van Remmen. “The weakness associated with it contributes to falls and fractures, deconditioning, institutionalization, and contributes to obesity and diabetes. All of these could significantly improve with a treatment.”
In the lab, Van Remmen showed that a new therapy, CDN1163, was successful in elderly mice.
They studied mice until they were 26-28 months old—approximately equivalent to 70-plus human years. They observed those who did not receive the treatment had normal atrophy and weakness, but those who did receive it maintained considerably more muscle mass and muscle function.
“Now that we know the drug works, we need to develop a more efficient version. Once we have refined it, we can then start moving toward human trials,” said Van Remmen, who holds the G.T. Blankenship Chair in Aging Research at OMRF. “This is very promising and could make a real impact in improving quality of life for veterans.”
Griffin also received $650,000 for his work in developing a new clinical approach for people suffering from osteoarthritis, the most common form of arthritis.
There are no approved treatments for osteoarthritis, or OA, which stems from the loss of cartilage in joints and abnormal bone growth. About half all Americans develop painful OA during the course of their lifetime.
“There is an urgent need for OA care, and it’s even more pronounced in veterans,” said Griffin. “They have a higher rate of post-traumatic OA than the general population related to injuries and the physical nature of their service.”
Clinical studies show being physically active reduces OA pain and increases mobility. “And it doesn’t matter what kind of activity you do. It can be swimming, walking, aerobics or other activities,” he said. “Being active in any way you can shows benefits, and we aim to understand exactly how exercise works at a molecular level.”
Using this clinical knowledge, Griffin will study how exercise changes the metabolism of joint tissues to reduce pain and inflammation. This should allow them to develop options to give OA sufferers more ‘bang for their buck’ with therapy, he said.
Their findings could also provide safer alternatives to opioids and non-steroidal anti-inflammatory drugs for reducing pain.
“Eventually we would love to treat the disease itself, but if we can efficiently reduce symptoms and pain, that would be a great interim success that could help veterans sooner rather than later,” said Griffin.

A change of weather and watching the grounds how they change. Jan Welch

It’s in March – but, we’ll be celebrating our 50th wedding anniversary. I think we’re going to make it. Nancy Markum

Ballgames with OU – football and then basketball season. Todd Markum

The only project I have going is feeding the ducks. Frank Kalies

Story by Darl DeVault and Robin Maxey

Caring for his mother, who provided one of the best starts in life he says, is routine at age 64 for Ted Cox, who set the record for the best hitting start in Major League Baseball. He moved from his family home in Midwest City he and his wife Debbie share, to a room in his mother’s home he grew up in 19 months ago to be her live-in caregiver.
His mother, Ernestine Cox, is 91 years old and legally blind. His father Virgil died in January of 2013 at 94.
Every day, Cox helps dress and feed her. His son Joe and his wife Samantha also aid in this effort. Cox usually prepares her to travel the two miles on the three days a week she receives dialysis at a center in Midwest City.
She receives physical therapy twice a week in the home and has difficulty remembering life’s details, such as taking her medicine. Some days Cox has to remind her of her schedule, such as when the nurse will arrive and the home health worker to bathe her.
Cox began as the caregiver to his parents by assuming these same duties for a year before his father died. He says he is happy to assume these duties, as his mother gave him one of the best starts any son could ask for in Midwest City in the early 1960s. His mother took him to practices when Cox started playing sports at seven years old.
“I can afford to take care of my mom while my wife Debbie since 1974 is much happier of the two of us to still be working.” Cox said recently. “My mom supported us kids in our sports and I had some baseball talent that allowed me to have a little more life experience than most. Giving her this personal care is all a part of being a good son to a loved one.”
Cox said every year during September, he hears from his circle of friends who remind him about his baseball record. This also makes him think how blessed his start in life was, with his mother’s support.
His mother made sure Cox made it to football and basketball practices before he settled on baseball. While learning to play baseball in school, he was also a three-sport star. He was the starting quarterback and point guard for his high school basketball team.
He became one of the best high school baseball players in Oklahoma by his senior year in 1973. His outstanding play on the Midwest City High School baseball team catapulted him into the Boston Red Sox farm system right out of high school.
There he was fortunate to have another mentor help him have a great start. Future National Baseball Hall of Famer Ted Williams, known as the greatest hitter ever in MLB history, taught him to hit even better.
Williams was a Red Sox special coach every Fall in the Florida Instructional League who showed Cox plenty of attention. Cox climbed the minor-league ladder, stepping up a class each year under Williams watchful eye.
“From first meeting Williams in 1974 at Fall Instructional (League) after first joining the Red Sox, the importance of those conversations really began during my first big league spring training in 1976,” Cox said last week. “Williams liked to hang out at the batting cages observing our swings, sometimes making really loud comments over the background noise.”
The legendary Williams’ suggestions had an immediate impact on the young athlete’s future. “Williams showed me and strongly suggested I try a couple of things,” Cox said. “Those tips certainly helped as I saw instant improvement in my ability to drive the ball into the outfield.”
He became a more productive and powerful hitter throughout his climb thanks to Williams’ coaching. At 6-foot-3 and 195 pounds by 1977, he evolved into a skilled hitter with a major-league swing with the help of coaches Williams and Johnny Pesky.
William “Ted” Cox started his MLB career for the Boston Red Sox with a best of all-time hitting performance in September of 1977. Cox established the MLB rookie debut hitting record by hitting safely in his first six at-bats in his first two games. Of the 19,000 players who have started MLB careers, his six consecutive hits at the start of his career is still the record for 150 years of organized baseball, 42 seasons later.
“Successful hitters have extraordinary eyesight, reflexes and reaction time to go with great hand-eye coordination,” Cox said. “But all that won’t get you on base unless you hit the ball. For that you need real major league coaching to help you develop a swing so fluid that every pitch they want to throw is your favorite pitch to hit.”
He went on the play five years and for two other teams, the Seattle Mariners and Toronto Blue Jays. Forty-two years later Cox is retired and living in the family home he grew up in while taking care of his mother Ernestine in Midwest City.
Writer’s Note: In celebration of the Washington Nationals winning their first World Series in franchise history Wednesday night, Senior News and Living provides baseball fans the full story of Ted Cox’s historic first two games online in an expanded version of this story. Please go to okveterannews.com for full details of each of his first six hits.

Dear Savvy Senior, Because of my mobility problems, I’m thinking about getting a walk-in bathtub that’s easy to get into and out of but could use some help selecting one. What can you tell me about walk-in tubs, and can you recommend some good companies that make and install them?  Bubble Bath Betty

Dear Betty,
Walk-in tubs are a good option for mobility challenged seniors because they’re much easier to get into and out of than a standard tub, and will help prevent slips, trips and falls too. Here’s what you should know. The Basics
Walk-in bathtubs are uniquely designed tubs that have a watertight, hinged door built into the side of the tub that provides a much lower threshold to step over (usually 2.5 to 7 inches) versus a standard tub that’s around 15 inches.
In addition to the low threshold, most walk-in tubs also have a built-in seat, grab bars, anti-slip floors, anti-scald valves and a handheld showerhead. And many higher-end models offer therapeutic spa-like features that are great for seniors with arthritis and other ailments.
The kind of tub you choose will depend on your needs, preferences and budget, and the size and layout of your bathroom. The cost of a walk-in tub today with professional installation ranges anywhere from $3,000 to $10,000. Here are some other things you’ll need to consider, to help you make a good choice.
Tub size: Walk-in bathtubs vary in size. Most models have high walls between three and four feet high, and are between 28 and 32 inches wide, but will fit into the same 60-inch long space as your standard tub without having to reconfigure the room. There are also bariatric walk-in tubs that have wider door openings and larger seats to accommodate people over 300 pounds.
Wheelchair-accessible: Most walk-in tubs have an inward opening door, but if you use a wheelchair, an outward opening door may be a better option because they’re easier to access.
Tub options: The most basic and least expensive type of walk-in tub you can get is a simple soaker tub. But depending on your preferences, you have many other options like an aerotherapy (air jets) tub, hydrotherapy (whirlpool water jets) tub, aromatherapy tub that mixes fragrant essential oils with the water, or a combination tub that has multiple features. Also, look for tubs that have an in-line heating system to keep your bathwater warm while you soak.
Fast fill and drain: One drawback to using a walk-in bathtub is that the bather must sit in the tub as it fills and drains, which can make for a chilly experience. To help with this, consider a tub that has fast-filling faucets and pump-assisted drainage systems, which significantly speed up the process. But these options may require some plumbing modifications to your bathroom.
Easy cleaning: Keeping the tub clean should be a priority, especially if you get a therapy tub because of the bacteria that can grow in it. So, look for tubs with self-cleaning systems.
Warranty: The best walk-in bathtubs on the market today are made in the USA. Also make sure the company you choose has a lifetime “leak-proof” door seal warranty and lengthy warranties on both the tub and the operating system.
Where to shop: While there are many companies that make, sell and install walk-in bathtubs, some of the best in the industry are American Standard (AmericanStandard-us.com), Safe Step (SafeStepTub.com) and Kohler (KohlerWalkinBath.com). Most companies offer financing with monthly payment plans.
Unfortunately, original Medicare does not cover walk-in bathtubs nor do Medicare supplemental (Medigap) policies, but some Medicare Advantage plans may help pay. There are also many states that offer Medicaid waivers that will help pay for the purchase and installation of a walk-in tub to those that qualify, and the VA offers some programs that provide financial aid too.
To get started, contact a few companies who will send a local dealer to your home to assess your bathroom and give you product options and estimates for free.
Send your senior questions to: Savvy Senior, P.O. Box 5443, Norman, OK 73070, or visit SavvySenior.org. Jim Miller is a contributor to the NBC Today show and author of “The Savvy Senior” book.

Free Zoo admission offered to active duty, veteran members of the military all month

November is Military Appreciation Month at the Oklahoma City Zoo and Botanical Garden, and as a thank you for their service, the Zoo is honoring active duty, retired and veteran members of the military, National Guard and Reserves with free general admission for the entire month. Plus, up to four immediate family members of qualifying individuals will receive 50% off of general Zoo admission on date of visit. Military members must show valid military ID to receive complimentary admission.
“Our servicemen and women put their lives on the line for us and it’s an honor to recognize their sacrifice and welcome them to the Zoo,” said Dwight Lawson, OKC Zoo CEO/executive director. “We want to offer those who have been away from their families for months at a time a great experience and a chance to rediscover their connection to nature and their connections to one another.”
Military members will also enjoy 40% off concessions and merchandise at the Zoo’s Safari Gift Shop and get $10 off all available Wild Encounter behind-the-scenes experiences. Plus, they can save on the Zoo’s premiere ticket options:
· Zoo-It-All (access to rides, experiences, feedings and shows): $16/adult, child and senior (Mon.-Sun.)
· Ride-It-All (access to train, carousel and tram): $10/adult, child and senior (Fri.-Sun.)
Also during November, Zoo guests can show their wildlife pride with an exclusive red, white and blue bison conservation wristband. The bison is America’s National Mammal and a guest favorite at the Zoo’s Oklahoma Trails habitat. The limited-edition design is exclusively available during Military Appreciation Month. The conservation wristband is $2 with 100% of proceeds supporting the Zoo’s Round Up for Conservation program.
The Zoo is proud to support military members the rest of the year with a 50% discount on general admission to all veterans, active duty, active reserves and retirees of the military (with valid military ID). This discount does not apply to children or dependents of veterans, active duty, active reserves or retirees of the military.
The Zoo salutes service with Military Appreciation Month this November! Located at the crossroads of I-44 and I-35, the Oklahoma City Zoo is a proud member of the Association of Zoos and Aquariums, the American Alliance of Museums, Oklahoma City’s Adventure District and an Adventure Road partner. Hours of operation are 9 a.m. to 5 p.m. daily. Regular admission is $11 for adults and $8 for children ages 3-11 and seniors ages 65 and over. Children two and under are admitted free. Stay up-to-date with the Zoo on Facebook, Twitter, Instagram and YouTube by visiting Our Stories. Zoo fans can support the OKC Zoo by becoming Oklahoma Zoological Society members at ZOOfriends.org or in-person at the Zoo! To learn more about these and other happenings, call (405) 424-3344 or visit okczoo.org.

by Greg Schwem

Elizabeth Warren, exactly what do you eat for breakfast?
There must be something in your cereal, your eggs, your breakfast smoothie, or whatever it is you start your day with, that allows you to take selfies with strangers for four hours AFTER you’ve completed the stump speech that you hope propels you to the nation’s highest office in 2020.
If I posed for that many photos, my first act as president would be to lock myself in the White House, alone, and not come out for four years. Want my signature on a bill? Just slip it under the Oval Office door and wait patiently. Eventually, I’ll push it back out. Along with an executive order banning selfies.
In your case, calling the photos “selfies” is misleading, for it implies that every one of your fans held their own phones, extended their arms, took the pictures themselves, viewed them with disappointing looks and said, “Wait, can we do one more? In landscape mode?”
Your loyal subjects hand their phones to a staff member who takes the photos. Other celebrities use similar methods. Two years ago, I was one of 1,500 fans who waited in a Chicago bookstore for over three hours simply to meet and take a photo with Bruce Springsteen. A member of The Boss’ security team took my iPhone and held the photo button down continuously for about five seconds. I was left with 10 pics, including one of Springsteen welcoming his next fan while my rear end exited the stage. I deleted that one.
Truthfully, I’ve never understood the desire to take, and post, photos of oneself, regardless of the background or situation. Several times a year I open my social media feeds to find someone has snapped a “hospital bed selfie,” taken just before the subject sees an emergency room physician or undergoes an operation. Invariably, the photos are accompanied with text such as, “Guess where I am?” as if the hospital gown wasn’t a clue. Seriously, what kind of medication makes a person think, “Hmmm, I have a tube in my nose, a needle in my arm and all my body hair has been shaved. DAMN, I LOOK GOOD!”
But the chance to rub shoulders with celebrities and come away with proof is a different story. My Bruce pic is on my office wall and elicits cries of, “Whoa, you met Springsteen?” from most who see it. Mere seconds after taking the photo, I posted it to all my social media feeds and happily read the comments expressing awe and jealousy. I’m sure 1,499 others were doing the same thing that day.
So, Sen. Warren, I understand your strategy. The more pics of you floating around cyberspace with everyday Americans, the greater your likability. I doubt President Trump even knows what a selfie is. Then again, it’s impossible to snap a photo while simultaneously tweeting and golfing.
But senator, are you sure this is the right strategy? With all those people waiting in line, chances are excellent at least one of them is a pedophile, a Ponzi scheme creator or a future school shooter. In 1978, after serial murder John Wayne Gacy was arrested, a photo emerged of him posing with First Lady Rosalynn Carter, taken just seven months prior. Oops.
Of course, you can’t possibly know the backgrounds of everyone waiting to smile with you, but would that stop vicious memes from circulating? Would it stop the hosts at Fox News from plastering that photo onscreen every time they mention your name? Doubtful.
I have yet to decide who among the Democratic candidates will receive my vote. But Sen. Warren, I do admire your grass-roots approach, not to mention your stamina. If you win, thousands upon thousands of Americans will be able to say they met the president of the United States.
Let’s hope they all know how to back up their iPhones.
(Greg Schwem is a corporate stand-up comedian and author of two books: “Text Me If You’re Breathing: Observations, Frustrations and Life Lessons From a Low-Tech Dad” and the recently released “The Road To Success Goes Through the Salad Bar: A Pile of BS From a Corporate Comedian,” available at Amazon.com. Visit Greg on the web at www.gregschwem.com.) (c) 2019 GREG SCHWEM. DISTRIBUTED BY TRIBUNE CONTENT AGENCY, LLC