story and photo by Bobby Anderson, Staff Writer

A cough. A sniffle.
You feel something coming on. But what next?
You can call your doctor and hopefully get an appointment sometime in the next couple weeks.
Or you can get in your car and head to the local urgent care clinic and wait with 20 or 30 others doing the same thing.
What if there was a better way?
That’s what Dr. Mark Prather thought in 2013 when he came up with a unique service model that would eventually become DispatchHealth.
“Really anything you can think of you would get in your car and go to urgent care for but more,” Dispatch Community Engagement Manager Tiffany Traxler said, explaining the service that has recently expanded into the metro.
DispatchHealth is bringing back the house call with a modern technology twist. DispatchHealth gives patients ways to access convenient, high-quality acute care in the comfort of their home at the time of need.
DispatchHealth is redefining the healthcare landscape as an extension of a patient’s healthcare team and offering solutions for simple to complex medical problems all from the comfort of your home.
The concept dates back to 2013 when Prather was running the emergency department in Denver for Centura Health.
“They asked Dr. Prather if he could come up with a system that could be delivered safely in the home for patients who go to the emergency room with urgent needs but not emergent,” Traxler explained. “He knew the need and he knew how to make things mobile.”
“He started going out on calls.”
Working with the ambulance service through the 911 system, Prather helped more than 400 patients in 18 months in the comfort of their own homes.
The total cost savings to the health system was more than $1 million.
But saving patients the time, expense and hassle of an ER visit was priceless.
The model has spread like wildfire to Colorado Springs, Richmond, Phoenix, Las Vegas, Houston, Oklahoma City, Tacoma, Dallas and Springfield.
Blue Cross and Blue Shield – one of Oklahoma’s largest insurers – quickly saw the value.
“Blue Cross and Blue Shield saw what we were doing and the impact we were making,” Traxler said. “For the 65-and-under patient if you have Blue Cross and Blue Shield it’s an urgent care co-pay. For 65 and up all Medicare, Medicaid and Medicare Advantage plans … we bill as an urgent care.”
For some that can mean an urgent care visit in their home for less than $50.
Services include testing such as: blood tests on-site, strep test, flu swab, urinalysis, urine cultures, stool culture, test for blood in stool, pregnancy test, lactate, 12-lead EKG, PT/INR, rapid infectious disease testing and more.
Dispatch also provides medications such as: anti-inflammatories, IV antibiotics, IV fluids, prednisone, lasix, antiemetics, flu medications, laxatives, stool softeners, heartburn prevention, glucose gel, anesthetics, migraine cocktail, antihistamines and more.
IVs can be placed and fluids begun all in your home.
Breathing treatments can also be administered.
AVOID THE BUG
Last year’s influenza outbreak was one of the worst in nearly a decade and the severity of the outbreak was extreme. In fact, The Center for Disease Control and Prevention (CDC) recorded over 20,000 positive flu tests per week at the height of the outbreak.
While most seek treatment at an emergency room (ER) or urgent care clinic, when leaving one’s home the virus can be immediately exposed to others and cause further spread of the flu. Also, ERs and clinics can easily become overwhelmed with a high number of sick patients during flu season, leading to overcrowding, lengthy wait times and even physician burnout.
Adults can infect others one day before their flu symptoms even develop and can pass on the virus up to a full week after becoming sick.
“Flu comes on very, very quickly. If it’s 2 p.m. and you realize you don’t feel well you’re not going to get into your (doctor’s office),” DispatchHealth Market Director Amy Evans said. “With flu if you can get those anti-virals within that first day or two it cuts down on the length of flu.”
“When you’re talking about the elderly population and people with compromised immune systems that 12 hours means something.” To request on-demand urgent care brought to you call 405-213-0190

by Bobby Anderson, Staff Writer

A sociologist, a psychologist and a benedictine nun walk into a room.
Sounds like the beginnings of a good joke.
But for John Karlin, PhD, those are just a few of the cast of characters that helped create his new book: Fear, Religion, Politics: Well I’ll Be Darn!
Karlin spent the last year of his life writing this book that takes a look at the intertwining of three things deeply personal to Americans.
“It was incredible in the sense that how much insight humans have but not realize it,” Karlin said. “In researching this I kept seeing these little lights in other people’s works.”
Karlin was aided by Dr. Melvyn Preisz, Rhonda Bell, Judy Martin, Marsha McMillin, Gerry Lantagne and others in developing his second book. Each brought their own unique talents.
Preisz is a local clinical psychologist who befriended Karlin years ago.
“I agree with Dr. Karlin’s timely and insightful assessments of this unprecedented crisis,” Preisz said. “From my own psychological viewpoint, these enemies of our individual freedoms collude to divide and conquer the good within us, and to continue to attack our personal conscience from a buffet of lies.”
Karlin stresses he has no political motives with this book.
His wish for what readers walk away with is simple.
“Simply an understanding of those undercurrents, a complete, full, intense understanding of … what’s actually happening underneath the surface,” Karlin said. “I just expose those undercurrents, that was my whole concern. I write from a sociological perspective.”
“I’m not the only one who has picked up on this. What I found is pieces of those themes in many, many other works.”
Karlin cites some 120 references in his work, that he says was a labor love performed with dear friends.
“Our intent was to give seniors out there a message that you can do stuff like this. You’re never too old,” the 72-year-old Karlin said. ”Don’t just sit, you’re capable of doing stuff.”
More than 20 years of Karlin’s life have been spent in teaching, largely at Northwestern Oklahoma State in Alva, Oklahoma City University and Phillips University.
While teaching sociology and criminal justice at OCU, Karlin begin his friendship with Preisz.
Preisz introduced him to Lantagne, who introduced Martin, a former Benedictine nun and things began falling into place.
“It was just friends introducing friends,” Karlin said. “It was basically happenstance then realized ‘Gosh, look at all this talent.”
The motives were simple.
“I just didn’t like the way things were going in this country especially politically and socially in terms of the turmoil and discontent,” Karlin said. “I thought there had to be something underneath that. As a sociologist you always know that what’s on the surface isn’t always the whole story.”
“Sometimes in our culture there are some very deep undercurrents that help explain.”
Karlin recalled attending Louisiana State University for his doctorate. A conversation with an old fisherman came to mind.
The fisherman pointed to the Mississippi River and told Karlin to watch it closely.
“It’s just real slow, old man river kind of thing but underneath that is just incredible turmoil,” Karlin said. “The Mississippi in spots is almost a mile deep and a lot of people don’t realize that because the undercurrent is cutting it.”
“There are literally complete trees down there. That’s the way culture and society can be.”
That got Karlin thinking about what’s underneath today’s politics and headlines.
“What’s under that is not good,” he said.
Karlin’s book flows through three sequences with the first being our innate fear of death and how we view our own mortality.
“And how that came to actually produce the phenomena we call religion in society,” Karlin said. “Any religion, it doesn’t matter what it is, came from the fear of death because religion was a way to escape that tension and fear.”
The second sequence evaluated Christianity and the life of Jesus Christ.
“I looked at what (Jesus Christ) was actually trying to accomplish in his own time and he was trying to accomplish something,” Karlin said. “You’ll find that as somewhat of a shocker.”
The third sequence takes things into the political realm.
“That’s where the dream goes awry because a big chunk of our Christian community want to blend religion and politics to the point where they are no longer distinguishable and that’s not good,” Karlin said.
“That’s what has created most of the problems you see in society today. Basically, it’s the drive towards theocracy.”
Karlin’s book is now available on Amazon. He will do a benefit book signing for the Peace House at the Peace Festival at the Civic Center Music Hall November 10 from 10 a.m. to 4 p.m.
The Peace House will get $5 for every book sold.

Dear Savvy Senior, Can you provide some tips on how to choose a good estate sale company who can sell all the leftover items in my mother’s house?  Inquiring Daughter

Dear Inquiring,
The estate sale business has become a huge industry over the past decade. There are roughly 22,000 estate sale companies that currently operate in the U.S., up nearly 60 percent from just 10 years ago. But not all estate sale companies are alike.
Unlike appraisal, auction and real estate companies, estate sale operators are largely unregulated, with no licensing or standard educational requirements. That leaves the door open for inexperienced, unethical or even illegal operators. Therefore, it’s up to you to decipher a good reputable company from a bad one. Here are some tips to help you choose.
Make a list: Start by asking friends, your real estate agent or attorney for recommendations. You can also search online. Websites like EstateSales.net and EstateSales.org let you find estate sale companies in your area.
Check their reviews: After you find a few companies, check them out on the Better Business Bureau (BBB.org), Angie’s List (AngiesList.com), Yelp (Yelp.com) and other online review sites to eliminate ones with legitimately negative reviews.
Call some companies: Once you identify some estate sale companies, select a few to interview over the phone. Ask them how long they’ve been in business and how many estate sales they conduct each month. Also find out about their staff, the services they provide, if they are insured and bonded and if they charge a flat fee or commission. The national average commission for an estate sale is around 35 percent, but commissions vary by city and region.
You may also want to ask them about visiting their next sale to get a better feel for how they operate. And be sure to get a list of references of their past clients and call them.
Schedule appointments: Set up two or three face-to-face interviews with the companies you felt provided you with satisfactory answers during the phone interviews.
During their visit, show the estate liquidator through the property. Point out any items that will not be included in the sale, and if you have any items where price is a concern, discuss it with them at that time. Many estate companies will give you a quote, after a quick walk through the home.
You also need to ask about their pricing (how do they research prices and is every item priced), how they track what items sell for, what credit cards do they accept, and how and where will they promote and market your sale. EstateSales.net is a leading site used to advertise sales, so check advertising approaches there.
Additionally, ask how many days will it take them to set up for the sale, how long will the sale last, and will they take care of getting any necessary permits to have the sale.
You also need to find out how and when you will be paid, and what types of services they provide when the sale is over. Will they clean up the house and dispose of the unsold items, and is there’s an extra charge for that? Also, make sure you get a copy of their contract and review it carefully before you sign it.
For more information on choosing an estate sale company, see National Estate Sales Association online guide at NESA-USA.com, and click on “Consumer Education” then on “Find the Right Company.

Send your senior questions to: Savvy Senior, P.O. Box 5443, Norman, OK 73070, or visit SavvySenior.org. Jim Miller is a contributor to the NBC Today show and author of “The Savvy Senior” book.

by Bobby Anderson, Staff Writer

To say Mike Isaac’s resume is extensive would be an understatement.
EMT, police officer, detective, SWAT team member – all of it has combined into Isaac’s RN Nurse Manager role at JD McCarty Center for Children with Developmental Disabilities in Norman.
And for the past six years now, Isaac has been a nurse. But his past is almost as interesting as his present.
Fellow nurse manager Suanne Livingston likes working alongside Isaac and is constantly amazed by his background.
“He’s very organized and he’s very respected,” Livingston said. “He does a great job with staff. When he was a staff nurse he was a great staff nurse. I kind of defer to him as far as how he handles things employee-wise because he’s a little more hard-nosed than I am.”
“I learn a lot from him and I kind of watch and learn how he handles situations.”
Isaac worked in emergency rooms at night to help put him through college. He applied for PA school and quickly found it wasn’t a career track he wanted to pursue.
He spent some time in medical research and a couple other jobs before signing on with the Norman Police Department as an EMT for the ambulance service.
He attended the prerequisite police academy and later pursued his master’s degree. The only problem was working those 24-hour EMT shifts really took a toll on his studies.
So he decided to become a police officer instead.
“I said I would just transfer over and I did,” Isaac said. “I did really well and got promoted quickly and did a bunch of really good stuff but I got really interested in things involving mental health.”
A detective and eventually a supervisor, Isaac helped craft Norman’s policy on dealing with mental health subjects. His plans were carried over into department’s across the nation during his 27 years with Norman PD.
Isaac’s reputation earned him a spot helping craft officer-involved shooting policy.
“They weren’t getting the help they needed post-shooting,” Isaac said. “There were a lot of trauma victims involved with homicide and rape – two of the things I was assigned to – that weren’t getting follow-up care to prevent and treat post traumatic stress.”
Working with the FBI’s Behavioral Science unit in Quantico, Va., he helped craft policy to protect all involved.
“You didn’t take their gun right after a shooting. You took it as evidence but you replaced it,” Isaac said. “You didn’t put them on a desk job and treat them like they were unable to do work. Basically we wrote it so they would get a return to work slip.”
The process helped officers work through the ensuing mental and physical issues while protecting their personal health information. Inservice training was given and officers qualified again at the shooting range before easing back into their duties while riding with a supervisor.
“That was actually taken to Quantico for the national FBI academy that all law enforcement agencies around the world send people to.
“Our policy is still given out there.”
A friend mentioned he would be a perfect fit for nursing school.
“They sold me on this BADNAP program,” Isaac said of Oklahoma City Community College’s accelerated nursing program. “It was a great program. I wouldn’t do it again but it was a great way to get in and get employed and get out. I had a couple jobs before I even graduated.”
EMT, policeman, mental health advocate – you would think it all prepared him for nursing school.
“It did, but the pace was a great equalizer. It was just so fast. I don’t know how some of those people did it,” Isaac said. “I don’t know how some of those people did it, single heads of households with children to take to soccer games and other things.
“They were my heroes throughout. It was a great experience.”
Day and night, Isaac completed his ADN in eight months.
“It was tough but it was good. They don’t cut any corners,” Isaac said.
Assessment, investigation, report writing and observation – all skills Isaac honed in his former life have prepared him for a nursing career.
Nursing care plans are still vital. Different disciplines are heavily involved such as dietary and physical therapy.
He laughs when he admits his experience as Norman’s chief hostage negotiator still comes in handy.
But most days he doesn’t need it.
“The opportunity to see mostly the direct care staff grow in professionalism and responsibility so they can take ownership,” Isaac said of his greatest reward. “I always tell them when I interview it’s not a nursing home for kids.”

Expanding and strengthening their team and service

SYNERGY HomeCare proudly opened their doors over 5 years ago in Edmond, Oklahoma. Weama Kassem, CEO and President of SYNERGY HomeCare, has always dreamt of having a business that centered around caring for others; specifically, our aging community. Weama has been fortunate enough to attract a team of professionals with the same heartfelt drive and talent. The people Weama has assembled have accomplished some incredible things by always putting their clients’ needs and happiness first. The SYNERGY HomeCare team always refers to each other as “SYNERGY Family” and they work together to create an atmosphere of care and respect for each other and for their clients and families.
Weama opened her second office in December 2016 in Norman, Oklahoma. This enabled the company to reach and connect a larger clientele and reaching beyond Edmond and Oklahoma City. One of the most essential guidelines in opening the new location has been to duplicate their high standard of care. SYNERGY HomeCare does not use contracted caregivers, all are employees who must completed in-house training, along with continued monthly and quarterly training programs. This ensures the caregivers are not only qualified, but it strengthens the support and bonds within the company itself. Each caregiver is a Certified Nursing Assistant and/or a Certified Home Health Aide. They are each insured and bonded by SYNERGY HomeCare and strive to provide excellent care and support to both clients and their families.
SYNERGY HomeCare is very pleased to announce that Jeff Aynes has joined the SYNERGY Home Care Team as our Director of Sales and Marketing. Jeff has been a strong advocate for health care in Oklahoma for many years and will make a great leader on our team. Jeff is a father of two beautiful ladies and grandfather of two beautiful girls. He went to the University of Central Oklahoma and Oklahoma State University where he studied Marketing, Public Relations, and Broadcasting. Jeff is a Past President of Marketing Plus for Healthcare and currently serves as Secretary. He is currently serving as President of the Northside Marketing Alliance, as well as, Secretary. He has served in the community for many years as a member of the Shriner’s, Scottish Rite, Eastern Star, Amaranth, and Masons where he is a Past Master. He has been volunteering with Muscular Dystrophy, Cerebral Palsy Association, and Make Promises Happen Camp for over 25 years. His passion outside of Sales and Marketing is music. He has owned Jammin’ Jeff Entertainment for over 25 years and has performed over 1,800 events. Jeff joins the SYNERGY staff from AllianceHealth Midwest where he served as Director of Marketing for the Behavioral Health Program. Prior to going to AHM, Jeff served for over 5 years at Absolute Senior Care of Oklahoma City and A Premier Senior Home Care of Tulsa as their Director. We are beyond thrilled and honored that Jeff has chosen to join our team and know he is truly a valuable asset that will provide wonderful support to our growing company.
Together, Weama and Jeff, will be able to provide assistance to our aging community, education to our referral partners, knowledge to our team of growing caregivers, and a bright and smiling face to see each time you encounter them. Serving people is what SYNERGY HomeCare does every day and it is truly the drive and passion of both Weama and Jeff. With over 100 caregivers and five years in business, the SYNERGY HomeCare team stands ready to answer specific questions about care.
Whether you are a senior living on your own, with an aging spouse, or you have an aging parent – there are some key things to keep in mind when selecting a home care company. First, is the home care company licensed in the state? Companies are reviewed annually to determine their eligibility, and this is a perfectly normal question to ask a potential company. Ask to see a copy of their business license. Second, ask if the caregivers are employed by the company instead of being contract labor employees. It may seem beneficial to contract our work, but actually you can face many liability and scheduling issues down the road. Ask the provider to include client AND their family members in developing the plan of care. SYNERGY HomeCare has full-time RNS on staff to specifically build a plan of care for each new client and they spend the time you need to sort out every little detail. Lastly, ask for a list of references so you can check in on who you are considering to employ! We are all use to providing references when applying for a job. SYNERGY HomeCare is happy to answer questions like these anytime.
SYNERGY HomeCare is a group of Oklahomans that you can trust. Weama, Jeff, and the whole team are honored to provide care to this amazing community and welcome your call anytime, day or night!

SYNERGY HomeCare is located at 13720 N Bryant Ave. Edmond, OK 73013 405-254-3046
www.synergyhomecareedmond.com

Oklahoma State Department of Health (OSDH) Interim Commissioner Tom Bates has appointed Dr. Edd Rhoades as Chief Medical Officer for the agency. Dr. Rhoades has been with the agency for 40 years and is currently serving as the Medical Director for Family Health Services.
“Dr. Rhoades has served the state and this agency with integrity in a number of key positions over the years and it is appropriate that he should be the first person to fill this important role,” said Commissioner Bates. “The establishment of a Chief Medical Officer aligns with the public health structure of many other states and will provide guidance to our core mission.”
The Oklahoma State Board of Health approved creation of the position at their Sept. 14 meeting, following a recommendation that was included in a corrective action plan provided to the legislature in January. The Chief Medical Officer will advise agency leadership on medical and public health issues and provide medical oversight and consultation to agency service areas and county health departments. Under the current organizational structure, the Office of the Commissioner continues to focus on improving the financial operation and organization of the agency to ensure efficient delivery of core services.
A graduate of the University of Oklahoma School of Medicine, Dr. Rhoades also holds a Masters of Public Health in Health Administration from the University of Oklahoma College of Public Health. He is a Diplomate of the American Board of Pediatrics and has received numerous awards for his work in maternal and child health and environmental protection. Among his honors are the Joan K. Leavitt, M.D. Award from the Oklahoma Public Health Association and the Mike Synar Environmental Excellence Award.
“I’m looking forward to working with Commissioner Bates and the senior leadership team to provide guidance for the agency as we continue to focus on issues that will improve the health of all Oklahomans,” said Dr. Rhoades. “I’m honored to have this opportunity to share my experiences and promote the great work being done by all of our public health professionals.

The holiday season is approaching, and the Oklahoma City Fire Department has a few safety tips for your family and friends. A small fire can double in size every 30-60 seconds. Following these safety messages will provide a safer winter and holiday season. The holiday season is approaching, and the Oklahoma City Fire Department has a few safety tips for your family and friends. A small fire can double in size every 30-60 seconds. Following these safety messages will provide a safer winter and holiday season. Smoke Alarms· Working smoke alarms should be placed inside and outside each bedroom and sleeping area. Install smoke alarms on every level of the home including basements. The Oklahoma City Fire Department has a “Project Life” smoke alarm program. Firefighters will install smoke alarms at no charge for qualifying residents of Oklahoma City. Contact information 405-316-2337, www.smokealarmsokc.com or www.Gratisalarmasokc.com.  Residents outside of Oklahoma City can contact your local fire department or Red Cross. · Test smoke alarms once a month while practicing your escape plan. Practice your escape plan based on your mobility and always have a meeting place outside the home. · Replace batteries once a year. When replacing the 9-volt battery consider upgrading to a 10-year lithium battery smoke alarm.· Replace all smoke alarms after 10 years or before expiration date located on the backside. · People with hearing impairment can contact the Oklahoma Assistive Technology Foundation (OkAT), 888-885-5588 or email abletech@okstate.edu.     OkAT will install smoke alarms with strobe lights and bed shaker for qualifying Oklahoma residents. Apply at www.okabletech.okstate.edu. * According to the National Fire Protection Association (NFPA), “3 out of 5 fire deaths happen in homes with no smoke alarms or the alarms are not working.”Heating Safety·Keep space heaters a minimum of 3-feet away from anything that can burn. The 3-foot clearance must include people and pets. Never use extension cords with space heaters. Plug them directly into the outlet and ensure the space heater is the only item plugged into the outlet. Turn off and unplug when not in use or going to bed. ·Heating systems and chimneys should be inspected and cleaned every year by a qualified professional. Schedule your inspection and cleaning before use.  ·Keep metal fireplace screens or heat-tempered glass secured and in the correct position when in use. Discard cool ashes from the fireplace into a metal container. Keep the metal container at least 10-feet from your home.  ·Never use ovens, stove top, or open burning to heat your home. Open flame heat sources should have a venting system. The use of alternative heating sources inside your home could have deadly consequences caused by carbon monoxide poisoning or fire. ·Always follow the manufacturer’s instruction. ·Install Carbon Monoxide (CO) alarms outside each sleeping area and on every level of the home.      *According to NFPA, “Half of home heating fires are reported during the months of December, January, and February.”Holiday Safety·Don’t block exits with decorations. ·Follow manufacturer’s instruction and do not overload extension cords. ·Keep candles away from children and pets. ·Ask smokers to smoke outside. Wet all cigarette butts before discarding. ·Never leave food cooking on the stovetop unattended. Make sure you are alert when cooking. ·Cut 2 inches off the base of a live Christmas tree before placing in the stand. Add water to your tree stand daily. Don’t put heating sources or candles near the Christmas tree. Always turn off Christmas tree lights before leaving home or going to bed. ·Immediately remove the Christmas tree from inside your home after the holidays or when it is dry.  *According to NFPA, “Two of every five home decoration fires are started by candles.”Additional fire safety information is available at www.nfpa.org/Public-Education.
This is the first of a series of safetey articles provided by  Oklahoma City Fire Department, Oklahoma County Sheriff Department and the Oklahoma City Police Department.

The March of Dimes Oklahoma Chapter recently honored an OU Medicine nurse at its annual Nurse of the Year awards. Mandy Nelson, APRN in the medicine specialty unit at OU Medical Center, was named Nurse of the Year in the Advanced Practice category.
The Oct. 4 event celebrated nurses in more than a dozen categories, all of which were nominated by colleagues, supervisors or families they have served, according to the March of Dimes website. A selection committee of health care professionals selects the most outstanding nurse in each category.
Two additional OU Medicine nurses, Callie Tkach, RN in the NICU at The Children’s Hospital, and Susie Jones, APRN and Vice President of Quality/Safety and Nursing Practice at OU Medicine, were finalists in the Neonatal/Pediatric and Advanced Practice categories, respectively.
“Mandy and our finalists, Callie and Susie, are incredibly deserving of this honor,” said Cathy Pierce, Chief Nurse Executive at OU Medicine. “Our nurses work tirelessly to improve the lives of our patients and families. They truly represent the best in their fields and the best of OU Medicine.”

Scientists at the Oklahoma Medical Research Foundation have broken new ground in understanding how the lymphatic system works, potentially opening the door for future therapies.
The lymphatic system is a network of vessels and lymph nodes that spans the entire body. It is critical for good health and for the body to function properly. Defects in lymphatic vessels cause lymphedema, a disease characterized by dramatic and painful swelling in the limbs that often leads to infections.
Lymphedema can result from congenital mutations, surgery, radiation treatment for cancer or infection, and there is currently no cure. In addition to lymphedema, defects in the lymphatic system have been linked to a wide range of health consequences: cancer, atherosclerosis, Alzheimer’s disease and obesity.
Sathish Srinivasan, Ph.D., and Boksik Cha, Ph.D., at OMRF previously discovered that a particular pathway—known as the Wnt signaling pathway—regulates the development of the human lymphatic vascular system. In new research, published in the journal Cell Reports, they’ve found “the nuts and bolts of this important pathway.”
“We have identified the signaling molecules that activate this pathway,” said Srinivasan. “We also have learned which cells produce the signaling molecules, how they are sensed by the cells and how they are used in lymphatic development.”
Srinivasan was recruited to OMRF from St. Jude’s Children’s Research Hospital in 2013. His lab at OMRF has already identified several target genes for lymphedema. Srinivasan said that, after further study, this new information could eventually help researchers develop better therapeutic options for lymphedema and associated disorders.
“This signaling pathway has proved difficult to study, because it is complex and so little is known about how it functions normally, let alone when it goes wrong,” said Srinivasan. “Wnt signaling is aggravated and increased in breast cancer and colon cancer, but it is deregulated in diseases like Alzheimer’s and lymphedema.”
Srinivasan said drug companies are interested in finding molecules that can be targeted, either to promote or inhibit Wnt signaling, depending on the disease. “Our goal is to find whether such drugs could be used to treat humans with lymphedema and see if their disease can be managed, made less severe or even cured,” he said.
Other OMRF researchers who contributed to this research were Xin Geng, Ph.D., Riaj Mahamud, Lijuan Chen and Lorin Olson, Ph.D.

What will be on your Thanksgiving plate? Norman Regional Hospital Auxiliary

Ham and dressing, gravy, green beans. Maybe a little turkey and hot rolls.

Derald Fendley

We’ll be eating off the same menu but my favorite is cornbread dressing.

Jan Fendley

The usual turkey and dressing but also rutabagas and red cabbage.

Jonnina Benson

Turkey and dressing with candied yams, and pumpkin pie with lots of whipped cream.

Dixie Hurd