The Oklahoma Medical Research Foundation is recruiting healthy volunteers to study whether a diabetes drug can slow aging.
OMRF scientist Benjamin Miller, Ph.D., is investigating how metformin impacts insulin sensitivity and its link to the biological processes of aging. The 12-week study will take place at the Harold Hamm Diabetes Center in Oklahoma City and is open to adults between the ages of 40-75 without chronic disease.
“Aging is the leading risk factor for all chronic diseases. If we can slow the process, we may simultaneously slow or prevent the onset of conditions like cancer, cardiovascular disease, Alzheimer’s and dementia,” said Miller, a physiologist in OMRF’s Aging and Metabolism Research Program.
Metformin is the world’s most prescribed diabetes drug and is believed to be effective at slowing aging. In a 2019 study, Miller found the drug to be less impactful for this purpose when combined with exercise in sedentary adults. By understanding how metformin impacts the cellular function of healthy volunteers in the absence of exercise, Miller hopes to further show who it can — and cannot — benefit.
Volunteers will undergo a health screening prior to enrollment. Those with known heart disease, diabetes, bleeding disorders, cancer or other major illnesses do not qualify for the study. Strict Covid-19 protocols will be followed to ensure participant safety.
Once admitted, visits may range from 10 minutes to five hours and will include blood draws, muscle biopsy, a bone density scan and an insulin sensitivity test. Participants will be compensated for time and travel, and metformin or placebo will be provided at no cost.
To participate or for more information, contact Oklahoma Shared Clinical and Translational Resources at 405-271-3480 or osctr@ouhsc.edu.
Funding for the research is provided by National Institute on Aging grant No. R01AG064951, a part of the National Institutes of Health.
The University of Oklahoma is an equal opportunity institution. IRB 10699

The crowd watched as Nelson and Lola Cresente enjoyed their first dance together, as a newly renewed husband and wife. Surrounded by friends, family and their healthcare team at Valir PACE the couple showed what love through adversity looks like.
Just months ago, Lola Cresente thought she would be planning a funeral for her husband Nelson, but instead she planned a vow renewal — celebrating their 28th anniversary.
It seemed impossible. Last fall, Nelson was hospitalized with COVID pneumonia. He refused a ventilator, opting to go home on hospice care.
“The doctor told me I was going to take him home to die,” Lola said.
“We even helped them call a priest,” said Ashley Henson, a nurse practitioner with Valir PACE, a program of all-inclusive care for the elderly. “It was that dire.”
But he refused to give up.
As his PACE provider, Henson made a few home visits to check on Nelson and Lola. The PACE program works in partnership with Medicare and Medicaid to provide at-risk seniors the care they need to stay as healthy as possible and living independently in their community.
It was during one of those visits that something miraculous seemed to have happened.
Lola was explaining to Henson and a nurse from Valir Hospice how a neighbor had stopped by the day before to pray over Nelson, specifically that his lungs would open.
“I listened to his lungs and his hospice nurse listened to his lungs. We looked at each other and were like, ‘We’re hearing air here. Air is moving,’” Henson said.
Within weeks he was moved off of hospice. He started using a portable oxygen machine. And he regained much of his independence.
Now, months later, the couple celebrates a love that they came so close to losing with a special ceremony to renew their vows.
It was a first for PACE, to host an event like this. Henson led the way, knowing it would create a special memory for everyone involved.
“I took it to the team and said they would like to do this and there was just a big cheer that erupted in the room,” Henson said.
“It was Valir that was beside me when he got sick and I couldn’t think of any better place to spend our anniversary than here,” Lola said.
PACE employees created a bouquet, a boutineere and floral decor for the Cresentes, another employee made them a wedding cake. Another member of the team served as the ceremony officiant. It was truly a special day.
Daphne Chapman, an RN with Valir Hospice, was one of the nurses who cared for Nelson when he first returned home. She was also able to attend the ceremony.
“It’s a tremendous improvement. He definitely was doing very poorly,” Chapman said. “It’s wonderful to get to see them renew their vows today. Very special.”
While it isn’t the case for every hospice patient, it’s something that can happen.
“Thinking their loved one is going to pass and then them rebounding and getting to spend more time with family, it’s a wonderful thing,” Chapman said.
Henson even offered an emotional toast at the event, saying how proud she was of the Cresentes for not giving up and battling for Nelson’s health.
“It has been the most inspiring love story in my life to see,” Henson said.
After their first dance, Nelson took a seat to enjoy a Groom’s Steak (instead of cake). A meat lover, steak was one of the things he missed during his battle with COVID pneumonia.
They also had cake and appetizers, provided by Valir PACE’s dietary team.
The Cresentes say they couldn’t have asked for a better celebration.
“We just appreciate it very much,” Nelson said. “For me, this is just unbelievable.”

At the September 19, 2024 Champions of Health Gala, presented by Blue Cross Blue Shield of Oklahoma, RSVP of Central Oklahoma, Inc., was honored to receive the 2024 Champion of Senior Health Award.
RSVP of Central Oklahoma, Inc., is an AmeriCorps Seniors program dedicated to improving the lives of adults age 55+ in Oklahoma County by connecting them with meaningful and rewarding community volunteer opportunities, and by fostering a culture of equity and unity based in service throughout the region and beyond.
“We are honored to be chosen as this year’s recipient of the Champion of Senior Health Award,” said Laura McRaniels, Executive Director of RSVP of Central Oklahoma, Inc. “Since 1973, RSVP has helped foster a sense of purpose, has built connections, and has provided an array of opportunities for retired and senior adults in central Oklahoma to employ their strengths, expertise, and interests in service to others, which in turn lifts up the entire community. Research has shown that volunteering has significant positive health outcomes, both for volunteers and for those receiving services. We are grateful to be able to work with such diverse, talented, and caring people to meet a wide range of needs in the community, and also for the support of AmeriCorps, United Way of Central Oklahoma, and our nonprofit community partners.”
Each year, Champions of Health recognizes and celebrates organizations and people working to improve health outcomes and equity throughout Oklahoma, with the senior health category specifically honoring innovative programs and inspiring people who are meeting the needs of older adults and equipping them to lead better, healthier lives.

FEMA recently announced that federal disaster assistance has been made available to the Muscogee (Creek) Nation and ordered federal aid to supplement the tribe’s efforts in the areas affected by the severe winter storm from Dec. 21-25, 2022.
Federal funding is available to the Tribal Nation on a cost-sharing basis for emergency work and the repair or replacement of facilities damaged by the severe winter storm.
Federal funding is also available on a cost-sharing basis for hazard mitigation measures.
Roland W. Jackson has been named the Federal Coordinating Officer for federal recovery operations in the affected areas. Additional designations may be made if requested and warranted by the results of further assessments.

Story by Darl Devault, Contributing Editor

Many seniors have read that Oklahoma City was built in a day, although historians will tell you that many facets of its rich Western Heritage have not been brought forward to today. That could not be truer than what is commonly thought of as Oklahoma City’s history.
“The world can find the real story of Oklahoma City online at The First Eight Months of Oklahoma City (okgenweb.net), which provides a factual account of the birth of Oklahoma City in its two halves,” said Larry Floyd, 69. The adjunct U.S. history teacher at OSU-OKC said in an interview, “Research often bears out far more detail and sometimes a more surprising history than what gets published in popular accounts of any historic event.”
Although more than 50,000 settlers swarmed into the 2-million-acre “Unassigned Lands” of central Oklahoma Territory during the land run of April 22, 1889, Oklahoma City was not built in a day, month, or even a year. (story continues below)

Most future Oklahoma City residents came in by train to the Oklahoma Station townsite, arriving from the north and the south. The train coming north from Purcell was one hour late to the central depot for the three largest railways in the Southwest: Rock Island, Katy, and Santa Fe.
Because of this Oklahoma City began as two cities. Soon known as Oklahoma City and South Oklahoma City, this instant Western heritage was energized by people seeking the last of the free land folks had moved west to settle. Part of that heritage was the abundance of land, a fact that complicated the city’s beginning.
Many settlers wanted to claim their 160 acres while living close to the new townsite since it featured transportation and water as the North Canadian River ran through it. The 22 packed railroad cars arriving an hour late from Purcell brought new residents to a townsite already filled by hundreds of new Oklahoma Cityans. They had already staked their claims after arriving first on the train from Guthrie.
Oklahomans have consistently proven themselves resourceful, so the late arrivals set about creating South Oklahoma south of the Oklahoma City townsite. For every description of people staking claims and securing lots, the same took place on a prairie south of Reno Avenue in the new South Oklahoma City.
When G.W. Patrick found the most desirable lots taken and unable to do any better, he staked two lots on the south side of block three. His fellow late arrivals from the train followed his lead.
On April 23, Patrick began surveying south from the section line at Reno Avenue as the Citizens’ Survey began working north. Encountering no conflicting surveys, Patrick’s crew laid out 35 blocks along seven streets, and settlers made adjustments as required.
By Saturday, April 27, the citizens of South Oklahoma elected Patrick mayor and a full slate of city officials. They also drafted and adopted a city charter. Oklahoma City to the north elected Capt. W.L. Couch as mayor on May 1.
According to the City Directory published by the Oklahoma Chief newspaper in August 1889, South Oklahoma contained approximately 1,300 residents compared with about 3,700 north of Reno Avenue in Oklahoma City. The commercial district was mainly in Oklahoma City (except for the south side of Reno Avenue) and was the most densely developed portion of the two cities.
During the 15 months of its separate existence, South Oklahoma City saw three months of public schools, two churches, construction of an ice factory, lumberyards, and hundreds of homes built.
On May 2, 1890, the U.S. Congress passed the Organic Act, which provided for the organization of Oklahoma Territory and governing municipal incorporation. A petition was accepted on July 15, 1890, consolidating Oklahoma City and South Oklahoma into Oklahoma City.
This info is available online at https://www.89ertrail.com/12/# .
Capitol Hill was incorporated as a city in 1905. By then, a strong sense of community and civic activity made this area an economic and cultural force remaining independent until it joined with Oklahoma City in 1911.
The southern part of Oklahoma City continued to provide space to grow in the decade of statehood in 1907, Oklahoma City became the nation’s fastest-growing city from 1900 to 1910 and the new state’s capitol city.
Oklahoma City’s first major park, Wheeler Park, was established on the banks of the North Canadian River in 1903. The park included extensive gardens and places to relax and picnic. In 1904 the city’s first zoo opened in the park. After two great floods swept down the river in 1923, wiping out Wheeler Park, the zoo was relocated. The playground, park, and baseball diamonds were restored.
Oklahoma City’s first airport was built in south Oklahoma City. In 1911, the Oklahoma City Municipal Airfield opened the skies for future travel. The airfield brought new opportunities and visitors to the city, and in 1941 it was rededicated as Will Rogers World Airport.
Oklahoma City has since capitalized on its strategic central location from its beginning to its present status as the crossroads of America. Just like its beginning as a railroad hub, it assumed the crossroads are our nation’s two main interstate highways (I-35 and I-40). They intersect in Oklahoma City and share the same roadway for two miles. Even before the interstate highway system, OKC gained from being on historic Route 66 from Chicago to Los Angeles.
Farmer-stockmen found the city’s location along the North Canadian River strategic and its railroad services a lifeline to the rest of the country. Once the area’s largest employer, the Oklahoma City Stockyards and its business district maintain a high profile, it is a tourist destination and unofficial Western heritage center. Although no longer a focal point for local slaughterhouses, the daily cattle auctions still make it the world’s largest stocker/feeder market.
The city has cultivated its place as the centrally located Western Heritage center. It hosts more horse-related shows and competitions each year than any city globally. The National Cowboy and Western Heritage Museum is the official steward of that Western heritage. After a recent expansion, it now houses the most extensive collection of Western art and Americana west of the Smithsonian.

SSM Health at Home is proud to announce the health ministry now offers hospice service to people living in Oklahoma City and surrounding communities including Canadian, Cleveland, Grady, Lincoln, Logan, McClain, Oklahoma, Pottawatomie and Seminole Counties.
On May 26, 2022, SSM Health at Home achieved accreditation through the Accreditation Commission for Health Care (ACHC), demonstrating the organization’s commitment to delivering high quality care through compliance with ACHC Accreditation Standards, Centers for Medicare & Medicaid Services’ Conditions of Participation and Oklahoma state regulations.
“We have been providing home health services to the greater Oklahoma City area for many years. Offering hospice care will allow us to be there for patients throughout their entire health care journey,” said Melody McCormick, Branch Manager for SSM Health at Home’s hospice services in Oklahoma. “Adding hospice services will allow us to focus on providing compassionate care and improve quality of life for our patients at a time when they need it the most.”
“We are honored to expand our services to patients and families who need us at one of the most difficult points in life and are blessed to have a tremendous team of staff ready to provide the best care possible,” said Denise (dg) Gloede, President of Post-Acute at SSM Health.
“Hospice is the ultimate form of comprehensive care at the end of life. It is the combination of exceptional medical service, compassion, dignity and faith. It is an essential part of SSM Health’s ministry and Mission,” said Dr. Waddah Nassar, SSM Health at Home Medical Director and SSM Health Medical Group family practice physician.
To learn more about how hospice care can provide support to you or your family, please call 405-231-3755 or visit ssmhealth.com/athome.